Morphometric Changes of Rat Testis after Subchronic Oral Lead Intoxication and D-Penicillamine Treatment
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چکیده
منابع مشابه
Morphometric Changes of Rat Testis After Subchronic Oal Lead Intoxication and D-Penicillamine Treatment
Purpose: The aim of this study was to assess the efficacy of D-Penicillamine in reducing lead induced morphometric changes in rat testis. Materials and Methods: Male adult rats were exposed to 0.4% lead acetate in drinking water for 8 weeks. After this period, 6 rats sacrificed and testes were removed to evaluate the effects of lead intoxication. The remained lead exposed rats were divided int...
متن کاملComparative Effect of Silymarin and D-Penicillamine on Lead Induced Hemotoxicity and Oxidative Stress in Rat
Background: This study was performed to investigate the adverse effects of acute lead intoxication on hemogram, erythrocyte osmotic fragility and oxidant/antioxidant status and the probable ameliorating effect of silymarin in comparison to d-penicillamine. Methods: Forty-eight albino rats were divided in 8 groups and received the following treatments in a 10 day experiment in Shahid Chamran ...
متن کاملcomparative effect of silymarin and d-penicillamine on lead induced hemotoxicity and oxidative stress in rat
background: this study was performed to investigate the adverse effects of acute lead intoxication on hemogram, erythrocyte osmotic fragility and oxidant/antioxidant status and the probable ameliorating effect of silymarin in comparison to d-penicillamine. methods: forty-eight albino rats were divided in 8 groups and received the following treatments in a 10 day experiment in shahid chamran uni...
متن کاملPolymyositis complicating D-penicillamine treatment.
Although there is good evidence that D-penicillamine can induce polymyositis, the exact pathogenic mechanism remains unclear. We report two patients with psoriatic arthritis and primary biliary cirrhosis respectively, who developed polymyositis while receiving D-penicillamine treatment for their primary diseases. Whether D-penicillamine treatment was the sole cause of polymyositis or acted as a...
متن کاملEffect of Lead Intoxication and D-Penicillamine Treatment on Hematological Indices in Rats Efectos de Intoxicación con Plomo y Tratamiento de D-Penicilamina en Índices Hematológicos en Ratas
Lead is a dangerous heavy metal which is widely spread in the environment. Lead content in the air, food and tap water has increased several folds during recent years due to extensive use of this metal in petrol, paints, battery and other industries (Tuormaa, 1995). Despite of attempts for reducing the exposure to this metal, there are still some reports of cases with severe lead toxicity (Hers...
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ژورنال
عنوان ژورنال: Pakistan Journal of Biological Sciences
سال: 2006
ISSN: 1028-8880
DOI: 10.3923/pjbs.2006.1310.1314